In 2006 she made her television debut on the show Barney and Friends.Ryan's first film role was in 2007 as a guest character in Barney: Let's Go to the Firehouse, she played the role of a teenager.
In 2009, Ryan landed a starring role in the independent feature film, What If..., alongside Kevin Sorbo and Kristy Swanson.
The film was shot in Grand Rapids and Manistee, Michigan in July 2009 and was released in theaters on August 20, 2010.
Ryan played one of the main characters, Bailey Pickett, on the Disney Channel Original Series, The Suite Life on Deck, which is a sequel to the hit Disney Channel series, The Suite Life of Zack & Cody.
The series's pilot aired on September 26, 2008 in the United States and it became the most watched series premiere in Canada on the Family channel.
Ryan was set to headline the "Terrific Teen Tour", a concert series which co-headlined Mitchel Musso, Jasmine Richards and Savannah Outen, that would start on July 9, 2009 and end on July 14 but the tour was canceled owing to schedule conflicts.